Description

1-[3-Fluoro-4-(Trifluoromethyl)Phenyl]Propylamine is a high-value fluorinated aromatic amine building block. This compound is critical for introducing specific fluorine-containing motifs into target molecules, which can dramatically alter their physicochemical and biological properties. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its unique structure enables the fine-tuning of lipophilicity, metabolic stability, and binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance bioavailability and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, improving chemical resistance, thermal stability, and surface properties.
• Advanced Material Research: Utilized in academic and industrial R&D for developing novel fluorinated compounds with specialized applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific fluorinated aromatic amine chemistry.

Basic Information

Product Name	1-[3-Fluoro-4-(Trifluoromethyl)Phenyl]Propylamine
CAS No.	473732-66-0
Molecular Formula	C10H11F4N
Molecular Weight	221.20 g/mol
Synonyms	3-Fluoro-4-(trifluoromethyl)phenethylamine; 1-[3-Fluoro-4-(trifluoromethyl)phenyl]propan-1-amine; 2-(3-Fluoro-4-(trifluoromethyl)phenyl)ethanamine; 3-Fluoro-α-methyl-4-(trifluoromethyl)benzenemethanamine; Benzenemethanamine, 3-fluoro-α-methyl-4-(trifluoromethyl)-; 1-(3-Fluoro-4-trifluoromethylphenyl)propylamine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of 1-[3-Fluoro-4-(Trifluoromethyl)Phenyl]Propylamine is analyzed to confirm identity, purity, and consistency. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing all test results are available upon request. Our quality management system supports the needs of cGMP and ISO-guided manufacturing for research and commercial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.