Description

(Rs)-1-[3-(Trifluoromethyl)Phenyl]Propylamine is a chiral amine building block of significant importance in advanced organic synthesis. Its core value lies in the trifluoromethylphenyl moiety, which is a key pharmacophore known to enhance the metabolic stability, lipophilicity, and binding affinity of bioactive molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Key chiral intermediate in the synthesis of pharmaceutical candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Building block for the development of agrochemicals, such as herbicides and fungicides, leveraging the properties of the trifluoromethyl group.
• Precursor for advanced material science applications, including the synthesis of specialty polymers and liquid crystals.
• Ligand precursor in asymmetric catalysis for the production of other enantiomerically pure compounds.
• Starting material for the research and development of novel fluorinated compounds in medicinal chemistry.

Basic Information

Product Name	(Rs)-1-[3-(Trifluoromethyl)Phenyl]Propylamine
CAS No.	473732-59-1
Molecular Formula	C10H12F3N
Molecular Weight	203.20 g/mol
Synonyms	(R)-1-[3-(Trifluoromethyl)phenyl]propan-1-amine; (R)-α-Methyl-3-(trifluoromethyl)benzeneethanamine; (R)-1-(3-Trifluoromethylphenyl)propylamine; (R)-3'-(Trifluoromethyl)phenethylamine, α-methyl-; (RS)-1-[3-(Trifluoromethyl)phenyl]propylamine; 1-(3-Trifluoromethylphenyl)propylamine (racemic); α-Methyl-3-(trifluoromethyl)phenethylamine
EINECS	Contact for details

Quality Control

Our (Rs)-1-[3-(Trifluoromethyl)Phenyl]Propylamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to guarantee consistent quality and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for enantiomerically enriched grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.