Description

3,5-Difluoro-4-(Methylthio)Benzaldehyde is a high-purity fluorinated aromatic aldehyde building block of significant interest in advanced organic synthesis. Its value lies in the strategic combination of fluorine atoms and a methylthio group, which allows for precise modulation of electronic properties and reactivity in target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides where fluorine substitution enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic materials, improving charge transport and thermal stability.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and asymmetric synthesis.
• Advanced Polymer Chemistry: Incorporated as a monomer or cross-linking agent to create high-performance polymers with specific dielectric or surface properties.
• Chemical Research & Development: A versatile scaffold for exploring new chemical reactions and creating libraries of fluorinated compounds for screening.

Basic Information

Product Name	3,5-Difluoro-4-(Methylthio)Benzaldehyde
CAS No.	473299-49-9
Molecular Formula	C8H6F2OS
Molecular Weight	188.20 g/mol
Synonyms	4-(Methylthio)-3,5-difluorobenzaldehyde; 3,5-Difluoro-4-methylthiobenzaldehyde; 3,5-Difluoro-4-(methylsulfanyl)benzaldehyde; 4-Methylsulfanyl-3,5-difluorobenzaldehyde; Benzaldehyde, 3,5-difluoro-4-(methylthio)-; 3,5-Difluoro-4-(methylmercapto)benzaldehyde
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-(Methylthio)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing batch-specific results. Our quality commitment supports applications requiring high-purity building blocks under cGMP and ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere for prolonged procedures to minimize oxidation risk. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.