Description

Fmoc-Phe-Leu-Gly-Oh is a protected tripeptide building block widely used in solid-phase peptide synthesis (SPPS). This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise control. It is particularly valuable for the pharmaceutical and biotechnology industries in the development of therapeutic peptides, diagnostic agents, and biochemical research tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential assembly of custom peptide chains, leveraging the Fmoc (9-fluorenylmethoxycarbonyl) protecting group strategy.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based drugs targeting various diseases.
• Bioconjugation: Serves as a component for creating peptide-protein or peptide-small molecule conjugates for targeted delivery systems.
• Biochemical Probes: Incorporation into labeled peptides used as tools for studying enzyme activity, receptor binding, and cellular processes.
• Combinatorial Chemistry Libraries: A building block for generating diverse peptide libraries for high-throughput screening in drug discovery.
• Academic & Industrial R&D: Fundamental research reagent for studying peptide structure, function, and stability.

Basic Information

Product Name	Fmoc-Phe-Leu-Gly-Oh
CAS No.	471908-60-8
Molecular Formula	C33H37N3O6
Molecular Weight	571.67 g/mol
Synonyms	Fmoc-Phe-Leu-Gly-OH; Fmoc-Phenylalanyl-Leucyl-Glycine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalanyl-L-leucylglycine; Fmoc-L-Phe-L-Leu-Gly-OH; Fmoc-Phe-Leu-Gly; Fmoc-FLG-OH; (9-Fluorenylmethyloxycarbonyl)-Phe-Leu-Gly; N-Fmoc-phenylalanylleucylglycine
EINECS	Contact for details

Quality Control

Our Fmoc-Phe-Leu-Gly-Oh is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our customers' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.