Description

4,6(1H,5H)-Pyrimidinedione, 1-(3-Chloro-4-Fluorophenyl)-5-[[5-(Dimethylamino)-2-Furanyl]Methylene]Dihydro-2-Thioxo- is a high-value, heterocyclic organic compound featuring a pyrimidinedione core substituted with thioxo, aryl, and furanyl groups. This complex molecular architecture makes it a critical advanced pharmaceutical intermediate (API intermediate) and a versatile scaffold for medicinal chemistry research. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly in oncology and antiviral research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Reagent: May be utilized in biochemical assays as a probe or inhibitor to study specific enzymatic pathways.
• Organic Synthesis: Acts as a versatile precursor for the preparation of more complex heterocyclic compounds and specialty chemicals.
• Agrochemical Research: Investigated for potential applications in the development of new active ingredients for crop protection.

Basic Information

Item	Details
Product Name	4,6(1H,5H)-Pyrimidinedione, 1-(3-Chloro-4-Fluorophenyl)-5-[[5-(Dimethylamino)-2-Furanyl]Methylene]Dihydro-2-Thioxo-
CAS No.	471848-60-9
Molecular Formula	C₁₇H₁₅ClFN₃O₂S
Molecular Weight	379.83 g/mol
Synonyms	1-(3-Chloro-4-fluorophenyl)-5-[(5-(dimethylamino)furan-2-yl)methylene]dihydro-2-thioxopyrimidine-4,6(1H,5H)-dione; 1-(3-Chloro-4-fluorophenyl)-5-((5-(dimethylamino)furan-2-yl)methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione; 471848-60-9; Thioxopyrimidinedione derivative; API Intermediate 471848-60-9
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure consistency and reliability for research and development purposes. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.