Description

(5E)-5-{[1-(5-Chloro-2-Methylphenyl)-2,5-Dimethyl-1H-Pyrrol-3-Yl]Methylidene}-1-(Prop-2-En-1-Yl)-2-Thioxodihydropyrimidine-4,6(1H,5H)-Dione is a sophisticated heterocyclic organic compound featuring a pyrrole-pyrimidinedione core structure. This molecule is of significant interest as a key pharmaceutical intermediate or advanced research chemical for the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical synthesis facilities engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its complex, functionalized scaffold.
• Chemical Biology Probe: Acts as a tool compound for investigating biological mechanisms and protein-ligand interactions in academic and industrial research.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating libraries of novel heterocyclic compounds.
• Process Development: Used in scaling up synthetic routes and optimizing production parameters for potential active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(5E)-5-{[1-(5-Chloro-2-Methylphenyl)-2,5-Dimethyl-1H-Pyrrol-3-Yl]Methylidene}-1-(Prop-2-En-1-Yl)-2-Thioxodihydropyrimidine-4,6(1H,5H)-Dione
CAS No.	470681-24-4
Molecular Formula	C23H22ClN3O2S
Molecular Weight	439.96 g/mol
Synonyms	5-[(1-(5-Chloro-2-methylphenyl)-2,5-dimethyl-1H-pyrrol-3-yl)methylene]-1-(2-propen-1-yl)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione; 1-Allyl-5-{[1-(5-chloro-2-methylphenyl)-2,5-dimethyl-1H-pyrrol-3-yl]methylidene}-2-thioxodihydropyrimidine-4,6(1H,5H)-dione; (5E)-1-Allyl-5-{[1-(5-chloro-2-methylphenyl)-2,5-dimethyl-1H-pyrrol-3-yl]methylidene}-2-thioxo-1,2,3,4-tetrahydropyrimidine-4,6-dione; 470681-24-4; Allyl-substituted pyrrolopyrimidinedione derivative; Thioxodihydropyrimidinedione intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS, IR), to ensure consistency and reliability for research and development purposes. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming batch-specific specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.