Description

5-Bromo-3-Fluoro-2-Methoxybenzaldehyde is a versatile and high-value halogenated aromatic aldehyde building block. Its molecular structure, featuring bromine, fluorine, and methoxy substituents, makes it a critical intermediate for synthesizing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing advanced active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS-targeted drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine and bromine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated organic electronic materials, contributing to improved performance in displays and lighting.
• Functional Dye & Pigment Chemistry: Employed in the creation of specialized dyes and pigments where halogen substitution fine-tunes color properties and lightfastness.
• Cross-Coupling Reactions: The bromine atom provides an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck), enabling rapid diversification of molecular scaffolds.
• Chemical Research & Development: A valuable reagent for academic and industrial research exploring new synthetic methodologies and material science applications.

Basic Information

Product Name	5-Bromo-3-Fluoro-2-Methoxybenzaldehyde
CAS No.	470668-70-3
Molecular Formula	C8H6BrFO2
Molecular Weight	233.04 g/mol
Synonyms	3-Fluoro-5-bromo-2-methoxybenzaldehyde; 2-Methoxy-5-bromo-3-fluorobenzaldehyde; 5-Bromo-3-fluoro-2-methoxy-benzaldehyde; Benzaldehyde, 5-bromo-3-fluoro-2-methoxy-; 470668-70-3
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Fluoro-2-Methoxybenzaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.