Description

n-Methyl 3,5-Difluoroaniline is a fluorinated aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and the methylated amine group, which are essential for modulating the biological activity, metabolic stability, and physicochemical properties of target molecules. This high-purity intermediate is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides where fluorine substitution enhances efficacy and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting technologies, improving performance and stability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific chemical resistance, thermal stability, or surface properties.
• Dye & Pigment Manufacturing: Acts as an intermediate for producing fluorinated dyes with enhanced color fastness and unique spectral characteristics.
• Research & Development: Essential for academic and industrial research exploring new fluorination chemistry and structure-activity relationships (SAR).

Basic Information

Product Name	n-Methyl 3,5-Difluoroaniline
CAS No.	470458-51-6
Molecular Formula	C7H7F2N
Molecular Weight	143.13 g/mol
Synonyms	N-Methyl-3,5-difluoroaniline; 3,5-Difluoro-N-methylaniline; 3,5-Difluoro-N-methylbenzenamine; 1-Methylamino-3,5-difluorobenzene; Benzenamine, 3,5-difluoro-N-methyl-; N-Methyl-3,5-difluorobenzenamine
EINECS	Contact for details

Quality Control

Our n-Methyl 3,5-Difluoroaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical properties is provided with every shipment to guarantee traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density	~1.2 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.