Description

4,6(1H,5H)-Pyrimidinedione, 5-[[4-Bromo-5-(Dimethylamino)-2-Furanyl]Methylene]Dihydro-1-(4-Methylphenyl)-2-Thioxo- is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure incorporating pyrimidinedione, furan, and thioxo functional groups. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers for developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially in oncology and antiviral research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Organic Synthesis Reference Standard: Serves as a high-purity standard for analytical method development and validation in QC laboratories.
• Biochemical Probe Development: Utilized in the design and creation of molecular probes for studying enzyme inhibition and cellular pathways.
• Fine Chemical Production: Intermediate for the scaled-up manufacture of specialized, high-value chemicals for the life sciences industry.

Basic Information

Product Name	4,6(1H,5H)-Pyrimidinedione, 5-[[4-Bromo-5-(Dimethylamino)-2-Furanyl]Methylene]Dihydro-1-(4-Methylphenyl)-2-Thioxo-
CAS No.	469902-28-1
Molecular Formula	C18H16BrN3O2S
Molecular Weight	418.31 g/mol
Synonyms	5-[(4-Bromo-5-(dimethylamino)-2-furanyl)methylene]-1-(4-methylphenyl)dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione; 1-(4-Methylphenyl)-5-[[4-bromo-5-(dimethylamino)-2-furanyl]methylene]dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione; CAS 469902-28-1; Thioxopyrimidinedione derivative; Bromo-dimethylamino-furanyl pyrimidinedione
EINECS	Contact for details

Quality Control

Our production of 4,6(1H,5H)-Pyrimidinedione, 5-[[4-Bromo-5-(Dimethylamino)-2-Furanyl]Methylene]Dihydro-1-(4-Methylphenyl)-2-Thioxo- adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure compliance with ICH guidelines. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and meet the exacting standards of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.