Description

4-Pyrimidineacetic Acid, 5-Amino-1,2,3,6-Tetrahydro-2,6-Dioxo-, Ethyl Ester (9Ci) is a high-purity, heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents, particularly in medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other bioactive molecules targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Employed in the research and synthesis of novel herbicides, fungicides, or plant growth regulators.
• Fine Chemical Synthesis: Acts as a specialized building block for creating complex heterocyclic compounds used in materials science or specialty chemicals.
• Bioconjugation & Probe Development: The reactive functional groups make it suitable for developing biochemical probes or for bioconjugation applications in diagnostic research.

Basic Information

Product Name	4-Pyrimidineacetic Acid, 5-Amino-1,2,3,6-Tetrahydro-2,6-Dioxo-, Ethyl Ester (9Ci)
CAS No.	467421-27-8
Molecular Formula	C9H11N3O4
Molecular Weight	225.20 g/mol
Synonyms	5-Amino-1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidineacetic acid ethyl ester; Ethyl 5-amino-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-acetate; 5-Amino-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-acetic acid ethyl ester; 4-Pyrimidineacetic acid, 5-amino-1,2,3,6-tetrahydro-2,6-dioxo-, ethyl ester; CAS 467421-27-8; 5-Amino-1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-acetic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 4-Pyrimidineacetic Acid, 5-Amino-1,2,3,6-Tetrahydro-2,6-Dioxo-, Ethyl Ester (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistent performance as a synthesis intermediate. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). This material may be hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.