Description

Tirofiban CAS NO 464175-13-1 is a potent, non-peptide glycoprotein IIb/IIIa receptor antagonist. This compound is a critical active pharmaceutical ingredient (API) used to inhibit platelet aggregation. It is essential for the formulation of anti-thrombotic medications, primarily targeting the prevention and treatment of acute coronary syndromes. Pharmaceutical manufacturers and research institutions engaged in cardiovascular drug development are the primary users of this high-purity compound.

Application

• Primary Active Pharmaceutical Ingredient (API) in antiplatelet injectable formulations.
• Research and development of novel anti-thrombotic therapies and drug delivery systems.
• Pharmacological studies investigating platelet function and arterial thrombosis.
• Manufacturing of generic pharmaceutical products following patent expiry.
• Reference standard for quality control and analytical method development in pharmaceutical labs.
• Pre-clinical and clinical trial material for cardiovascular drug candidates.

Basic Information

Product Name	Tirofiban
CAS No.	464175-13-1
Molecular Formula	C22H36N2O5S
Molecular Weight	440.60 g/mol
Synonyms	Tirofiban Hydrochloride; Aggrastat; L-700,462; MK-383; (S)-N-(Butylsulfonyl)-4-[4-(4-piperidinyl)butoxy]phenylalanine; N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine; Tirofiban HCl
EINECS	Contact for details

Quality Control

Our Tirofiban is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent pharmaceutical-grade specifications, including identity, purity, and impurity profile. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with relevant pharmacopeial standards (e.g., USP, EP) and in-house specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.