Description

2-Iodo-4-(Trifluoromethyl)Phenol is a versatile halogenated phenol derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both iodine and a trifluoromethyl group on the phenolic ring, makes it a valuable intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for targets requiring halogen-bonding interactions or enhanced lipophilicity.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides where the trifluoromethyl group improves biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the creation of advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing characteristics.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in research applications, leveraging the reactivity of the iodine atom.

Basic Information

Product Name	2-Iodo-4-(Trifluoromethyl)Phenol
CAS No.	463976-21-8
Molecular Formula	C7H4F3IO
Molecular Weight	287.01 g/mol
Synonyms	4-(Trifluoromethyl)-2-iodophenol; 2-Iodo-α,α,α-trifluoro-p-cresol; Phenol, 2-iodo-4-(trifluoromethyl)-; 2-Iodo-4-trifluoromethylphenol; 2-Iodo-α,α,α-trifluoro-4-cresol; 2-Iodo-4-(trifluoromethyl)phenol
EINECS	Contact for details

Quality Control

Our 2-Iodo-4-(Trifluoromethyl)Phenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity and quantify impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full transparency and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and transfers should be minimized under direct light exposure.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residue on Ignition	<0.1%
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.