Description

Pyrimidine, 4-Chloro-2-(1,1-Difluoroethyl)- is a high-purity, halogenated pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and difluoroalkyl substituents, makes it a valuable intermediate for creating novel compounds with tailored properties. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for antiviral and anticancer therapies.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Serves as a core structure for designing molecular probes and enzyme inhibitors in biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of complex, high-value specialty chemicals.

Basic Information

Product Name	Pyrimidine, 4-Chloro-2-(1,1-Difluoroethyl)-
CAS No.	463337-59-9
Molecular Formula	C6H5ClF2N2
Molecular Weight	178.57 g/mol
Synonyms	4-Chloro-2-(1,1-difluoroethyl)pyrimidine; 2-(1,1-Difluoroethyl)-4-chloropyrimidine; 4-Chloro-2-(1,1-difluoroethyl)pyrimidine; 463337-59-9; 4-Chloro-2-(difluoroethyl)pyrimidine; Pyrimidine, 4-chloro-2-(1,1-difluoroethyl)-; SCHEMBL21806227; 1-(4-Chloropyrimidin-2-yl)-2,2-difluoroethane
EINECS	Contact for details

Quality Control

Every batch of Pyrimidine, 4-Chloro-2-(1,1-Difluoroethyl)- is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.