Description

1-Naphthalenamine,7-Fluoro-1,2,3,4-Tetrahydro-,(1S)-(9Ci) is a chiral, fluorinated tetrahydro-1-naphthylamine derivative, a sophisticated organic building block of significant interest in advanced chemical synthesis. Its value lies in the precise stereochemistry and the strategic incorporation of a fluorine atom, which are critical for modulating the biological activity and physicochemical properties of target molecules. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing complex active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research where fluorinated compounds are prevalent.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances metabolic stability and bioavailability.
• Asymmetric Catalysis Ligand Precursor: The chiral amine structure makes it a valuable precursor for developing novel ligands used in asymmetric hydrogenation and other catalytic processes.
• Material Science Research: Employed in the synthesis of specialty chemicals and advanced organic materials, such as liquid crystals or organic semiconductors.
• Chemical Biology Probes: Utilized to create fluorinated probes and tags for studying biological mechanisms and enzyme interactions.

Basic Information

Product Name	1-Naphthalenamine,7-Fluoro-1,2,3,4-Tetrahydro-,(1S)-(9Ci)
CAS No.	462105-66-4
Molecular Formula	C₁₀H₁₂FN
Molecular Weight	165.21 g/mol
Synonyms	(1S)-7-Fluoro-1,2,3,4-tetrahydro-1-naphthalenamine; (S)-7-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine; (1S)-7-Fluoro-1,2,3,4-tetrahydro-1-naphthylamine; 7-Fluoro-(1S)-1,2,3,4-tetrahydro-1-naphthalenamine; (S)-7-Fluoro-1,2,3,4-tetrahydronaphthyl-1-amine; 7-Fluoro-(S)-1,2,3,4-tetrahydro-1-naphthylamine; (1S)-7-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine
EINECS	Contact for details

Quality Control

Our production of 1-Naphthalenamine,7-Fluoro-1,2,3,4-Tetrahydro-,(1S)-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical characterization, including chiral purity verification, to meet the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.