Description

N2-Fmoc-D-Ornithine CAS NO 461691-09-8 is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). It serves as a critical building block for the controlled introduction of the D-ornithine residue, enabling the creation of peptides with specific chirality and enhanced metabolic stability. This compound is primarily utilized by pharmaceutical researchers and fine chemical manufacturers in the development of therapeutic peptides, diagnostic agents, and complex biomolecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the automated synthesis of custom peptides.
• Pharmaceutical Research: Building block for novel peptide-based drug candidates, including antimicrobial peptides and hormone analogs.
• Bioconjugation: Used to introduce reactive side-chain amines (after deprotection) for linking peptides to other molecules, dyes, or solid supports.
• Chemical Biology Probes: Synthesis of labeled or modified peptides for studying protein-protein interactions and enzyme activity.
• Academic & Institutional Research: Fundamental research in peptide chemistry, asymmetric synthesis, and molecular biology.
• Process Development: Scaling up the production of specific peptide sequences for preclinical and clinical studies.

Basic Information

Product Name	N2-Fmoc-D-Ornithine
CAS No.	461691-09-8
Molecular Formula	C₂₀H₂₂N₂O₄
Molecular Weight	354.40 g/mol
Synonyms	Fmoc-D-Orn-OH; N-α-Fmoc-D-ornithine; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-aminopentanoic acid; D-Ornithine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-; Fmoc-D-Ornithine; N-Fmoc-D-ornithine; (R)-5-Amino-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)pentanoic acid
EINECS	Contact for details

Quality Control

Our N2-Fmoc-D-Ornithine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric excess, meeting the stringent requirements for peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and consistency for your research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be kept under anhydrous conditions. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (D-isomer)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.