Description

4,6-Dichloro-2-(4-Methoxy-Phenyl)-Quinazoline is a high-purity, advanced pharmaceutical intermediate with a defined quinazoline core structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in oncology and targeted therapy research. It is essential for R&D laboratories, process development chemists, and manufacturers in the pharmaceutical and fine chemical sectors seeking reliable, high-quality intermediates for scalable production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinazoline-based drug candidates, especially kinase inhibitors.
• Oncology Research: Used in the development and scale-up of targeted cancer therapies due to its specific molecular scaffold.
• Chemical Synthesis: Serves as a versatile building block for introducing the dichloro-methoxy-phenyl-quinazoline moiety into more complex molecules.
• Process Chemistry: Employed in route scouting and optimization for the commercial manufacturing of APIs.
• Academic & Contract Research: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Fine Chemical Production: Integral to the multi-step synthesis of specialized, high-value organic compounds.

Basic Information

Product Name	4,6-Dichloro-2-(4-Methoxy-Phenyl)-Quinazoline
CAS No.	461036-87-3
Molecular Formula	C15H10Cl2N2O
Molecular Weight	305.16 g/mol
Synonyms	2-(4-Methoxyphenyl)-4,6-dichloroquinazoline; 4,6-Dichloro-2-(4-methoxyphenyl)quinazoline; 4,6-Dichloro-2-(p-methoxyphenyl)quinazoline; Quinazoline, 4,6-dichloro-2-(4-methoxyphenyl)-; 461036-87-3; 4,6-Dichloro-2-(4-methoxy-phenyl)-quinazoline
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-2-(4-Methoxy-Phenyl)-Quinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.