Description

7-(3,4-Dimethoxyphenyl)-5-(4-methoxyphenyl)-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine is a high-purity, advanced pharmaceutical intermediate belonging to the fused triazolopyrimidine class of heterocyclic compounds. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. Pharmaceutical R&D teams and fine chemical manufacturers need this precisely characterized intermediate to ensure the integrity and efficacy of their final drug candidates and to streamline complex multi-step synthesis pathways.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and development of new therapeutic agents, especially in neurology and psychiatry.
• Organic Synthesis Building Block: Used in constructing complex heterocyclic frameworks for medicinal chemistry and drug discovery programs.
• Biochemical Research: Employed in academic and industrial laboratories for studying structure-activity relationships (SAR) and enzyme inhibition.
• Reference Standard: Provides a high-purity standard for analytical method development, quality control, and regulatory submissions.
• Agrochemical Research: Investigated as a potential intermediate for developing new crop protection agents with specific biological activity.
• Material Science Exploration: Explored for creating novel organic electronic materials due to its conjugated π-system and electron-donating methoxy groups.

Basic Information

Item	Detail
Product Name	7-(3,4-Dimethoxyphenyl)-5-(4-Methoxyphenyl)-4,7-Dihydro-[1,2,4]Triazolo[1,5-A]Pyrimidine
CAS No.	459418-22-5
Molecular Formula	C21H20N4O3
Molecular Weight	376.41 g/mol
Synonyms	7-(3,4-Dimethoxyphenyl)-5-(4-methoxyphenyl)-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine; 459418-22-5; 4,7-Dihydro-7-(3,4-dimethoxyphenyl)-5-(4-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyrimidine; [1,2,4]Triazolo[1,5-a]pyrimidine, 7-(3,4-dimethoxyphenyl)-5-(4-methoxyphenyl)-4,7-dihydro-; Triazolopyrimidine derivative CAS 459418-22-5
EINECS	Contact for details

Quality Control

Every batch of 7-(3,4-Dimethoxyphenyl)-5-(4-methoxyphenyl)-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine is manufactured and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to ensure compliance with your research or cGMP-grade requirements. Our analytical methods, including HPLC, NMR, and MS, are validated to guarantee reliable and reproducible results for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.