Description

2-((2-(4-(2-Hydroxyethyl)Piperazin-1-Yl)-2-Oxoethyl)Thio)-5,6-Dimethyl-3-Phenylthieno[2,3-D]Pyrimidin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly for its potential role as a key building block in the synthesis of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• API Development: Employed in the process development and scale-up of new Active Pharmaceutical Ingredients (APIs) requiring a functionalized thienopyrimidine core.
• Biochemical Research: Potential use as a tool compound or inhibitor in biochemical assays to study specific enzyme pathways or protein interactions.
• Custom Synthesis: A starting material for the contract synthesis of specialized, non-commercial compounds for client-specific research programs.

Basic Information

Product Name	2-((2-(4-(2-Hydroxyethyl)Piperazin-1-Yl)-2-Oxoethyl)Thio)-5,6-Dimethyl-3-Phenylthieno[2,3-D]Pyrimidin-4(3H)-One
CAS No.	457952-06-6
Molecular Formula	C24H28N4O3S2
Molecular Weight	484.63 g/mol
Synonyms	5,6-Dimethyl-3-phenyl-2-[[2-[4-(2-hydroxyethyl)-1-piperazinyl]-2-oxoethyl]thio]thieno[2,3-d]pyrimidin-4(3H)-one; Thieno[2,3-d]pyrimidin-4(3H)-one, 2-((2-(4-(2-hydroxyethyl)-1-piperazinyl)-2-oxoethyl)thio)-5,6-dimethyl-3-phenyl-; 2-({2-[4-(2-Hydroxyethyl)piperazin-1-yl]-2-oxoethyl}sulfanyl)-5,6-dimethyl-3-phenyl-3H-thieno[2,3-d]pyrimidin-4-one; CAS 457952-06-6
EINECS	Contact for details

Quality Control

Our 2-((2-(4-(2-Hydroxyethyl)Piperazin-1-Yl)-2-Oxoethyl)Thio)-5,6-Dimethyl-3-Phenylthieno[2,3-D]Pyrimidin-4(3H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and opened under controlled conditions to minimize exposure to moisture and light. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.