Description

Methyl 5-Methyl-4-Oxo-1,4-Dihydrothieno[2,3-D]Pyrimidine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the thienopyrimidine class of heterocyclic compounds. Its core value lies in serving as a critical building block for the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. This compound is essential for pharmaceutical companies and research institutions focused on developing new therapeutic agents, especially in areas such as kinase inhibition and targeted cancer therapies.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly those with thienopyrimidine scaffolds.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with potential therapeutic effects.
• Kinase Inhibitor Development: Serves as a core structural component for synthesizing potential inhibitors targeting various kinases, which are crucial in oncology and inflammatory disease pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental studies in heterocyclic chemistry and drug discovery methodologies.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	Methyl 5-Methyl-4-Oxo-1,4-Dihydrothieno[2,3-D]Pyrimidine-6-Carboxylate
CAS No.	457911-10-3
Molecular Formula	C9H8N2O3S
Molecular Weight	224.24 g/mol
Synonyms	Methyl 5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylate; 6-Carbomethoxy-5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine; Thieno[2,3-d]pyrimidine-6-carboxylic acid, 3,4-dihydro-5-methyl-4-oxo-, methyl ester; Methyl 5-methyl-4-oxo-1,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylate; 457911-10-3; Thienopyrimidine carboxylate derivative
EINECS	Contact for details

Quality Control

Our Methyl 5-Methyl-4-Oxo-1,4-Dihydrothieno[2,3-D]Pyrimidine-6-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up processes with reliable, traceable materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.