Description

n-(3-Bromophenyl)-4,6-Dichloropyrimidin-5-Amine is a high-purity, halogenated pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for research and development chemists requiring precise molecular scaffolds to construct complex active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by pharmaceutical, agrochemical, and specialty chemical manufacturers focused on creating novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyrimidine core.
• Material Science: Serves as a monomer or cross-linking agent in the creation of specialized polymers and advanced organic materials.
• Chemical Synthesis: Acts as a versatile electrophile in nucleophilic aromatic substitution (SNAr) reactions and metal-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Academic & R&D: Employed in university and institutional laboratories for methodological studies and the exploration of new heterocyclic chemistry.

Basic Information

Product Name	n-(3-Bromophenyl)-4,6-Dichloropyrimidin-5-Amine
CAS No.	454685-38-2
Molecular Formula	C10H6BrCl2N3
Molecular Weight	319.99 g/mol
Synonyms	5-Amino-4,6-dichloro-N-(3-bromophenyl)pyrimidine; 4,6-Dichloro-N-(3-bromophenyl)pyrimidin-5-amine; 3-Bromo-N-(4,6-dichloropyrimidin-5-yl)aniline; (3-Bromophenyl)-(4,6-dichloropyrimidin-5-yl)amine; 454685-38-2; N-(3-Bromophenyl)-4,6-dichloro-5-pyrimidinamine
EINECS	Contact for details

Quality Control

Our n-(3-Bromophenyl)-4,6-Dichloropyrimidin-5-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided to guarantee the material meets your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.