Description

4H-Cyclopentapyrimidin-4-One, 2-[[(4-Fluorophenyl)Methyl]Thio]-1,5,6,7-Tetrahydro- (9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• API Development: Used in process chemistry for the scale-up and optimization of synthetic routes leading to target active pharmaceutical ingredients.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the global pharmaceutical industry.
• Biochemical Tool Compound: Potential use in biochemical assays and as a probe for investigating specific biological pathways and enzyme inhibition.

Basic Information

Product Name	4H-Cyclopentapyrimidin-4-One, 2-[[(4-Fluorophenyl)Methyl]Thio]-1,5,6,7-Tetrahydro- (9Ci)
CAS No.	451487-18-6
Molecular Formula	C14H13FN2OS
Molecular Weight	276.33 g/mol
Synonyms	2-(((4-Fluorobenzyl)thio)-1,5,6,7-tetrahydro-4H-cyclopenta[d]pyrimidin-4-one; 2-[(4-Fluorobenzyl)sulfanyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-one; 2-[[(4-Fluorophenyl)methyl]thio]-1,5,6,7-tetrahydro-4H-cyclopenta[d]pyrimidin-4-one; 451487-18-6; 4H-Cyclopenta[d]pyrimidin-4-one, 2-[[(4-fluorophenyl)methyl]thio]-1,5,6,7-tetrahydro-; 2-((4-Fluorobenzyl)thio)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidine
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is subjected to rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.