Description

3-(5,6-Dimethyl-4-Oxo-4H-Thieno[2,3-D]Pyrimidin-3-Yl)-Propionic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique thienopyrimidine scaffold. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel, small-molecule therapeutic agents. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in drug discovery and development, particularly for targeting kinase-related pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory diseases.
• Research & Development: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core structural component in the multi-step manufacturing of potential drug candidates.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme inhibition and cellular signaling pathways.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial molecules for clinical trials.

Basic Information

Product Name	3-(5,6-Dimethyl-4-Oxo-4H-Thieno[2,3-D]Pyrimidin-3-Yl)-Propionic Acid
CAS No.	450394-89-5
Molecular Formula	C11H12N2O3S
Molecular Weight	252.29 g/mol
Synonyms	3-(5,6-Dimethyl-4-oxo-4H-thieno[2,3-d]pyrimidin-3-yl)propanoic acid; 4H-Thieno[2,3-d]pyrimidine-3-propanoic acid, 5,6-dimethyl-4-oxo-; 450394-89-5; Thieno[2,3-d]pyrimidine propionic acid derivative; 3-(5,6-Dimethyl-4-oxothieno[2,3-d]pyrimidin-3-yl)propionic acid
EINECS	Contact for details

Quality Control

Every batch of 3-(5,6-Dimethyl-4-Oxo-4H-Thieno[2,3-D]Pyrimidin-3-Yl)-Propionic Acid is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the exacting standards required for pharmaceutical R&D and cGMP manufacturing. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting purity, identity, and impurity profiles as determined by HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.