Description

Furo[2,3-D]Pyrimidine-6-Carboxylic Acid, 1,2,3,4-Tetrahydro-1-Methyl-2,4-Dioxo-3-(Phenylmethyl)-, Phenylmethyl Ester is a high-purity, complex heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents and bioactive molecules, particularly in medicinal chemistry research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially for targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Chemical Biology Probes: Serves as a core scaffold for developing enzyme inhibitors or receptor modulators for biological pathway analysis.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the production of active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Intermediate for creating specialized compounds used in agrochemicals or advanced material science.

Basic Information

Product Name	Furo[2,3-D]Pyrimidine-6-Carboxylic Acid, 1,2,3,4-Tetrahydro-1-Methyl-2,4-Dioxo-3-(Phenylmethyl)-, Phenylmethyl Ester
CAS No.	448965-94-4
Molecular Formula	C22H18N2O5
Molecular Weight	390.39 g/mol
Synonyms	Benzyl 1-methyl-2,4-dioxo-3-(phenylmethyl)-1,2,3,4-tetrahydrofuro[2,3-d]pyrimidine-6-carboxylate; 1-Methyl-3-benzyl-2,4-dioxo-1,2,3,4-tetrahydrofuro[2,3-d]pyrimidine-6-carboxylic acid benzyl ester; Furo[2,3-d]pyrimidine-6-carboxylic acid, 1,2,3,4-tetrahydro-1-methyl-2,4-dioxo-3-(phenylmethyl)-, phenylmethyl ester; Tetrahydrofuropyrimidine derivative; CAS 448965-94-4
EINECS	Contact for details

Quality Control

Our Furo[2,3-D]Pyrimidine-6-Carboxylic Acid Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for research and development applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to preserve stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.