Description

Methyl 2-Amino-4-(Trifluoromethyl)Pyrimidine-5-Carboxylate is a high-value pyrimidine derivative and a crucial synthetic intermediate in modern organic chemistry. Its core value lies in the trifluoromethyl group, which imparts desirable properties like enhanced metabolic stability and lipophilicity to final compounds, making it indispensable for advanced research and development. This compound is primarily sought by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents. Its precise structure offers a versatile scaffold for constructing complex heterocyclic systems.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, where the CF3 group enhances biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in academic and industrial labs for exploring new heterocyclic chemistry and creating specialized chemical libraries.
• Material Science Precursor: Potential intermediate in the development of advanced organic materials, such as ligands for catalysts or components for electronic materials.

Basic Information

Product Name	Methyl 2-Amino-4-(Trifluoromethyl)Pyrimidine-5-Carboxylate
CAS No.	448242-52-2
Molecular Formula	C7H6F3N3O2
Molecular Weight	221.14 g/mol
Synonyms	2-Amino-4-(trifluoromethyl)pyrimidine-5-carboxylic acid methyl ester; Methyl 2-amino-4-(trifluoromethyl)-5-pyrimidinecarboxylate; 5-Pyrimidinecarboxylic acid, 2-amino-4-(trifluoromethyl)-, methyl ester; 2-Amino-4-trifluoromethyl-pyrimidine-5-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Amino-4-(Trifluoromethyl)Pyrimidine-5-Carboxylate is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical R&D and production processes. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.