Description

2(1H)-Pyrimidinone,5-Acetyl-4-(2,4-Dimethoxyphenyl)-3,4-Dihydro-6-Methyl-(9Ci) is a high-purity, synthetically valuable dihydropyrimidinone derivative, serving as a critical advanced intermediate for complex organic synthesis. Its molecular architecture, featuring acetyl and dimethoxyphenyl substituents, makes it a versatile building block for constructing pharmacologically active scaffolds. This compound is primarily sought by research institutions and pharmaceutical development companies engaged in medicinal chemistry, particularly for the synthesis of novel heterocyclic compounds with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Reagent: Serves as a precursor for synthesizing more complex polycyclic heterocycles and fused ring systems.
• Chemical Reference Standard: Utilized as a high-purity analytical standard for method development and quality control in R&D laboratories.
• Agrochemical Intermediate: Potential intermediate in the synthesis of novel crop protection agents and pesticides.
• Academic Research: Employed in university and institutional research for studying heterocyclic chemistry reactions and mechanisms.

Basic Information

Product Name	2(1H)-Pyrimidinone,5-Acetyl-4-(2,4-Dimethoxyphenyl)-3,4-Dihydro-6-Methyl-(9Ci)
CAS No.	448230-95-3
Molecular Formula	C15H18N2O4
Molecular Weight	290.32 g/mol
Synonyms	5-Acetyl-4-(2,4-dimethoxyphenyl)-3,4-dihydro-6-methyl-2(1H)-pyrimidinone; 5-Acetyl-4-(2,4-dimethoxyphenyl)-6-methyl-3,4-dihydro-1H-pyrimidin-2-one; 4-(2,4-Dimethoxyphenyl)-5-acetyl-6-methyl-3,4-dihydropyrimidin-2(1H)-one; 5-Acetyl-4-(2,4-dimethoxyphenyl)-6-methyl-1,4-dihydropyrimidin-2-one; Dihydropyrimidinone derivative (CAS 448230-95-3); Biginelli reaction derivative; 9CI Index Name Compound
EINECS	Contact for details

Quality Control

Every batch of 2(1H)-Pyrimidinone,5-Acetyl-4-(2,4-Dimethoxyphenyl)-3,4-Dihydro-6-Methyl-(9Ci) is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), physical characteristics, and spectroscopic data (NMR, IR, MS) is provided with each shipment to support your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.