Description

3-Chloro-2,5-Difluoroaniline is a high-purity halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which allows for precise molecular modifications and the introduction of specific functional groups. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the chloro and fluoro substituents enhance biological activity and stability.
• Material Science Precursor: Employed in the synthesis of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for creating complex, high-performance colorants and pigments.
• Cross-Coupling Reactions: Serves as a valuable substrate in palladium-catalyzed reactions like Suzuki and Buchwald-Hartwig amination for constructing complex aromatic systems.
• Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.

Basic Information

Item	Details
Product Name	3-Chloro-2,5-Difluoroaniline
CAS No.	448193-95-1
Molecular Formula	C6H4ClF2N
Molecular Weight	163.55 g/mol
Synonyms	3-Chloro-2,5-difluorobenzenamine; 2,5-Difluoro-3-chloroaniline; Benzenamine, 3-chloro-2,5-difluoro-; 3-Chloro-2,5-difluoro-phenylamine; 3-Chloro-2,5-difluoroaniline (primary name); 448193-95-1 (CAS); 3-Cl-2,5-F2-C6H3NH2
EINECS	Contact for details

Quality Control

Our 3-Chloro-2,5-Difluoroaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment ensures the material meets the stringent requirements for use in regulated synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. This amine derivative should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.