Description

Phenol, 2-Fluoro-3-Methoxy-5-Methyl- (9Ci) is a fluorinated and methoxylated phenol derivative, a high-value specialty chemical building block prized for its unique substitution pattern. This compound matters for its role in facilitating complex molecular synthesis, particularly in the development of advanced materials and active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to introduce specific fluorine and methoxy functionalities into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for introducing fluorine atoms to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the fluorine and methoxy groups contribute to biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic cores in electronic display and lighting materials.
• Polymer Modification: Employed to synthesize specialty monomers for high-performance polymers with tailored thermal and chemical resistance.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions and as a protected phenolic unit in multi-step synthetic routes in academic and industrial laboratories.
• Fluorinated Dye & Pigment Intermediate: Acts as a starting material for developing colorants with enhanced lightfastness and unique spectral properties.

Basic Information

Product Name	Phenol, 2-Fluoro-3-Methoxy-5-Methyl- (9Ci)
CAS No.	447462-92-2
Molecular Formula	C8H9FO2
Molecular Weight	156.16 g/mol
Synonyms	2-Fluoro-3-methoxy-5-methylphenol; 3-Methoxy-5-methyl-2-fluorophenol; 5-Methyl-2-fluoro-3-methoxyphenol; 2-Fluoro-3-hydroxy-5-methylanisole; 2-Fluoro-5-methyl-3-methoxyphenol; 2-Fluoro-3-methoxy-5-methyl-1-hydroxybenzene; 1-Hydroxy-2-fluoro-3-methoxy-5-methylbenzene
EINECS	Contact for details

Quality Control

Our Phenol, 2-Fluoro-3-Methoxy-5-Methyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep container tightly sealed to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (GC)	≥96.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.