Description

2-Fluoro-3-Methoxyphenol is a fluorinated phenolic compound that serves as a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring both fluorine and methoxy substituents, enables precise modulation of electronic and steric properties in target molecules. This intermediate is particularly critical for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic cores for electronic materials, contributing to improved performance in display and lighting technologies.
• Polymer Chemistry: Acts as a monomer or modifier for engineering plastics and high-performance polymers, imparting specific thermal and chemical resistance properties.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways and creating novel fluorinated compounds for various applications.

Basic Information

Item	Detail
Product Name	2-Fluoro-3-Methoxyphenol
CAS No.	447462-87-5
Molecular Formula	C7H7FO2
Molecular Weight	142.13 g/mol
Synonyms	3-Methoxy-2-fluorophenol; 2-Fluoro-3-hydroxyanisole; 2-Fluoro-3-methoxy-1-hydroxybenzene; 1-Fluoro-2-methoxy-3-hydroxybenzene; 2-Fluoro-3-methoxyphenol; 2-Fluoroguaiacol; 3-Methoxy-2-fluorophenol; o-Fluoro-m-methoxyphenol
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Methoxyphenol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤10 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.