Description

1-[2-[2-Fluoro-4-(Trifluoromethyl)Phenyl]-4-Methyl-5-Thiazolyl]Ethanone is a high-purity, fluorinated heterocyclic compound characterized by its distinct thiazole and phenyl backbone. This specialized chemical serves as a critical advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated molecules for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of next-generation pesticides and herbicides, where the trifluoromethyl and fluoro groups contribute to improved efficacy and environmental profile.
• Organic Synthesis Building Block: Employed in complex organic reactions, including cross-coupling and cyclization, to construct sophisticated heterocyclic frameworks.
• Material Science Precursor: Investigated for the synthesis of specialty polymers and advanced organic electronic materials due to its unique electronic properties imparted by fluorine atoms.
• Chemical Biology Probe: Serves as a scaffold for developing molecular probes and inhibitors to study biological pathways and enzyme functions.

Basic Information

Product Name	1-[2-[2-Fluoro-4-(Trifluoromethyl)Phenyl]-4-Methyl-5-Thiazolyl]Ethanone
CAS No.	447406-74-8
Molecular Formula	C13H9F4NOS
Molecular Weight	303.28 g/mol
Synonyms	2-Fluoro-4-(trifluoromethyl)phenyl 4-methyl-5-acetylthiazole; 1-[2-[2-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]ethanone; 5-Acetyl-2-[2-fluoro-4-(trifluoromethyl)phenyl]-4-methylthiazole; 2-(2-Fluoro-4-trifluoromethylphenyl)-4-methyl-5-acetylthiazole; Ethanone, 1-[2-[2-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]-; 447406-74-8
EINECS	Contact for details

Quality Control

Our production of 1-[2-[2-Fluoro-4-(Trifluoromethyl)Phenyl]-4-Methyl-5-Thiazolyl]Ethanone adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to meet the rigorous standards required for cGMP and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be moisture-sensitive; ensure containers are sealed under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.