Description

Benzenesulfonyl Chloride, 4-[4-[4-(Trifluoromethyl)Phenyl]-2-Thiazolyl]- is a specialized sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its dual functional groups, enabling it to act as a versatile electrophile for introducing the sulfonamide moiety, a key pharmacophore in many active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole and sulfonamide groups.
• Material Science Research: Employed in the creation of novel polymers and functional materials with specific electronic or surface properties.
• Chemical Biology Probe Development: Acts as a reactive handle for labeling proteins or modifying biomolecules in proteomics and bio-conjugation studies.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for the production of high-value, custom-synthesized compounds for research and development.

Basic Information

Item	Detail
Product Name	Benzenesulfonyl Chloride, 4-[4-[4-(Trifluoromethyl)Phenyl]-2-Thiazolyl]-
CAS No.	446883-84-7
Molecular Formula	C16H9ClF3NO2S2
Molecular Weight	403.83 g/mol
Synonyms	4-[4-[4-(Trifluoromethyl)phenyl]-1,3-thiazol-2-yl]benzenesulfonyl chloride; 2-(4-(Trifluoromethyl)phenyl)thiazole-4-benzenesulfonyl chloride; 4-(4-(4-(Trifluoromethyl)phenyl)thiazol-2-yl)benzene-1-sulfonyl chloride; (4-(4-(4-(Trifluoromethyl)phenyl)thiazol-2-yl)phenyl)sulfonyl chloride; 4-(4-(p-Trifluoromethylphenyl)-2-thiazolyl)benzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our Benzenesulfonyl Chloride, 4-[4-[4-(Trifluoromethyl)Phenyl]-2-Thiazolyl]- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.