Description

Fmoc-Dab(Boc,Me)-OH is a protected, non-proteinogenic amino acid derivative essential for advanced peptide synthesis. This high-purity building block is critical for researchers and manufacturers requiring precise control over peptide structure and function, particularly in the development of complex biomolecules. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic institutions engaged in peptide-based drug discovery and development.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the sequential assembly of peptides on resin, especially in Fmoc-chemistry strategies.
• Peptide Drug Intermediate: Used in the synthesis of therapeutic peptides and peptidomimetics targeting various diseases.
• Research Chemical: Serves as a crucial reagent in academic and industrial laboratories for studying peptide structure-activity relationships (SAR).
• Bioconjugation: Employed in the design and synthesis of peptide-protein conjugates and other bioconjugates for diagnostic and therapeutic applications.
• Combinatorial Chemistry: A valuable building block for generating diverse peptide libraries used in high-throughput screening for drug leads.

Basic Information

Product Name	Fmoc-Dab(Boc,Me)-OH
CAS No.	446847-81-0
Molecular Formula	C26H32N2O6
Molecular Weight	468.55 g/mol
Synonyms	Fmoc-N-δ-Boc-N-β-methyl-L-2,4-diaminobutyric acid; N-α-(9-Fluorenylmethoxycarbonyl)-N-δ-(tert-butoxycarbonyl)-N-β-methyl-L-2,4-diaminobutyric acid; Fmoc-Dab(Me,Boc)-OH; Fmoc-L-Dab(Boc,Me)-OH; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-4-[(2-methyl-2-propanyl)oxycarbonylamino]butanoic acid; N-α-Fmoc-N-δ-Boc-N-β-methyl-L-diaminobutyric acid; Fmoc-MeDab(Boc)-OH
EINECS	Contact for details

Quality Control

Our Fmoc-Dab(Boc,Me)-OH is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive peptide synthesis applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals used in pharmaceutical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.