Description

Fmoc-L-Dap(Boc, Me)-Oh CAS NO 446847-80-9 is a protected amino acid derivative, specifically an Fmoc-protected L-diaminopropionic acid with orthogonal side-chain protection. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled incorporation of a unique diaminopropionic acid residue into peptide chains. It is essential for researchers and manufacturers in pharmaceutical development, biotechnology, and advanced materials science who require high-purity, structurally defined intermediates for creating complex peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the automated, sequential assembly of peptides on resin.
• Pharmaceutical Research & Development: Used in the synthesis of therapeutic peptides, peptide hormones, and drug candidates requiring diaminopropionic acid motifs.
• Bioconjugation and Labeling: Serves as a precursor for introducing reactive amine handles or specific functional groups into biomolecules.
• Peptidomimetic Design: Enables the creation of modified peptide analogs with enhanced stability, bioavailability, or biological activity.
• Combinatorial Chemistry Libraries: A valuable component for generating diverse libraries of peptide-based compounds for screening.
• Academic and Industrial Research: Fundamental reagent for studies in biochemistry, medicinal chemistry, and chemical biology.

Basic Information

Product Name	Fmoc-L-Dap(Boc, Me)-Oh
CAS No.	446847-80-9
Molecular Formula	C25H30N2O6
Molecular Weight	454.52 g/mol
Synonyms	Fmoc-L-2,3-diaminopropionic acid(Boc, Me)-OH; Fmoc-L-Dap(Boc,Me)-OH; N-α-Fmoc-N-β-Boc-N-γ-methyl-L-2,3-diaminopropionic acid; Fmoc-Dap(Boc-Me)-OH; (2S)-3-[[(2-methylpropan-2-yl)oxycarbonyl](methyl)amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid; Fmoc-L-Dap(M-Boc)-OH; Fmoc-L-Dap(Nγ-Boc, Nβ-Me)-OH; Fmoc-Dap(Boc,Me)-OH
EINECS	Contact for details

Quality Control

Our Fmoc-L-Dap(Boc, Me)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive applications like peptide synthesis. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.