Description

2-(4-Ethyl-Piperazin-1-Yl)-4-Oxo-4H-Pyrido[1,2-A]Pyrimidine-3-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its fused pyridopyrimidine core. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought after by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Development: Used in the research and process development stages for creating new active pharmaceutical ingredients with a pyridopyrimidine backbone.
• Chemical Biology Probes: Can be utilized in the development of molecular probes for studying biological mechanisms and target validation.
• Contract Manufacturing: Supplied to CDMOs for scale-up synthesis under current Good Manufacturing Practice (cGMP) conditions for clinical trial material production.

Basic Information

Product Name	2-(4-Ethyl-Piperazin-1-Yl)-4-Oxo-4H-Pyrido[1,2-A]Pyrimidine-3-Carbaldehyde
CAS No.	446830-03-1
Molecular Formula	C15H17N5O2
Molecular Weight	299.33 g/mol
Synonyms	2-(4-Ethylpiperazin-1-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxaldehyde; 2-(4-Ethyl-1-piperazinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxaldehyde; 4H-Pyrido[1,2-a]pyrimidine-3-carboxaldehyde, 2-(4-ethyl-1-piperazinyl)-4-oxo-; 446830-03-1; 2-(4-Ethylpiperazin-1-yl)-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 2-(4-Ethyl-Piperazin-1-Yl)-4-Oxo-4H-Pyrido[1,2-A]Pyrimidine-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.