Description

5-Pyrimidinecarboxylicacid,4-(2-Furanyl)-1,2,3,4-Tetrahydro-6-Methyl-2-Oxo-,1,1-Dimethylethylester(9Ci) is a high-purity, complex heterocyclic building block of significant interest in advanced organic synthesis. This compound, with CAS number 446252-22-8, is valued for its unique molecular architecture, which incorporates both pyrimidine and furan moieties, making it a versatile precursor for pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology & Probe Development: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways and enzyme functions.
• Material Science Precursor: Acts as a specialty monomer or additive in the research of advanced polymers and organic electronic materials.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, including novel cyclization and functionalization reactions.
• Custom Synthesis & Scale-Up: A key starting material for contract manufacturing organizations (CMOs) engaged in producing custom fine chemicals at various scales.

Basic Information

Product Name	5-Pyrimidinecarboxylicacid,4-(2-Furanyl)-1,2,3,4-Tetrahydro-6-Methyl-2-Oxo-,1,1-Dimethylethylester(9Ci)
CAS No.	446252-22-8
Molecular Formula	C16H18N2O4
Molecular Weight	302.33 g/mol
Synonyms	4-(2-Furanyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-5-pyrimidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-(furan-2-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate; 4-(2-Furyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-5-pyrimidinecarboxylic acid tert-butyl ester; 446252-22-8; 5-Pyrimidinecarboxylic acid, 4-(2-furanyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarboxylicacid,4-(2-Furanyl)-1,2,3,4-Tetrahydro-6-Methyl-2-Oxo-,1,1-Dimethylethylester(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if necessary. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.