Description

2-Bromo-5-Fluoro-4-Methoxy-Phenylamine is a high-purity, multi-functional aromatic amine building block of significant importance in advanced organic synthesis. Its unique halogenated and methoxylated structure makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated phenylamine core.
• Material Science Research: Serves as a building block for functional polymers, liquid crystals, and organic electronic materials due to its electron-donating amine group and halogen substituents.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of specialized, high-performance dyes and pigments.
• Cross-Coupling Reactions: An essential substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) for creating complex biaryl structures.
• Chemical Research & Development: A versatile reagent for exploring new synthetic pathways and creating compound libraries for high-throughput screening.

Basic Information

Product Name	2-Bromo-5-Fluoro-4-Methoxy-Phenylamine
CAS No.	445441-58-7
Molecular Formula	C7H7BrFNO
Molecular Weight	220.04 g/mol
Synonyms	2-Bromo-5-fluoro-4-methoxyaniline; 4-Amino-2-bromo-5-fluoroanisole; 2-Bromo-5-fluoro-4-methoxybenzenamine; 1-Amino-2-bromo-5-fluoro-4-methoxybenzene; Benzenamine, 2-bromo-5-fluoro-4-methoxy-; 2-Bromo-5-fluoro-p-anisidine; 4-Methoxy-2-bromo-5-fluoroaniline
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Fluoro-4-Methoxy-Phenylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.