Description

3-(1,1-Difluoroethyl)- Benzenemethanol is a versatile fluorinated aromatic alcohol building block of significant interest in advanced organic synthesis. Its core value lies in the introduction of a difluoroethyl-substituted benzyl alcohol moiety, which is crucial for modulating the physicochemical and metabolic properties of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used as a precursor in the development of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in advanced display technologies.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, improving their chemical resistance, thermal stability, and surface properties.
• Organic Electronic Materials: Utilized in the synthesis of charge-transport or emissive materials for organic light-emitting diodes (OLEDs) and other electronic devices.
• Complex Ligand Synthesis: Acts as a starting material for chiral ligands used in asymmetric catalysis.

Basic Information

Product Name	3-(1,1-Difluoroethyl)- Benzenemethanol
CAS No.	444921-50-0
Molecular Formula	C9H10F2O
Molecular Weight	172.17 g/mol
Synonyms	[3-(1,1-Difluoroethyl)phenyl]methanol; 1-[3-(Hydroxymethyl)phenyl]-1,1-difluoroethane; m-(1,1-Difluoroethyl)benzyl alcohol; α,α-Difluoro-3-methylbenzyl alcohol (ambiguous, verify structure); Benzenemethanol, 3-(1,1-difluoroethyl)-; 3-(Difluoroethyl)benzyl alcohol
EINECS	Contact for details

Quality Control

Our 3-(1,1-Difluoroethyl)- Benzenemethanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.