Description

Boc-L-Lys(Dde)-Oh is a protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound is specifically engineered to provide orthogonal protection for the lysine side chain, enabling the sequential and selective assembly of complex peptides. It is a critical building block for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing peptide-based therapeutics, diagnostics, and research tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, sequential coupling of amino acids, particularly where selective side-chain deprotection is required.
• Pharmaceutical Research & Development: Used in the synthesis of novel peptide drug candidates, including hormones, antibiotics, and targeted therapies.
• Bioconjugation: Serves as a precursor for creating peptide-protein or peptide-small molecule conjugates for drug delivery systems.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive peptides.
• Peptide Antigen Production: Facilitates the synthesis of specific peptide sequences for antibody generation and immunological studies.
• Academic & Industrial Research: A fundamental reagent for studying protein structure-function relationships and peptide chemistry methodologies.

Basic Information

Product Name	Boc-L-Lys(Dde)-Oh
CAS No.	444795-66-8
Molecular Formula	C₂₂H₃₉N₃O₆
Molecular Weight	457.57 g/mol
Synonyms	Nα-Boc-Nε-(1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl)-L-lysine; Boc-Lys(Dde)-OH; (S)-2-((tert-Butoxycarbonyl)amino)-6-(1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethylamino)hexanoic acid; Boc-L-Lysine(Dde)-OH; Nα-Boc-Nε-Dde-L-lysine; Fmoc-Lys(Dde)-OH precursor; Dde-protected Boc-L-lysine; Orthogonally protected lysine derivative
EINECS	Contact for details

Quality Control

Our Boc-L-Lys(Dde)-Oh is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification, to ensure it meets the high standards required for peptide synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.