Description

4-Nitro-D-Phenylalanine Hydrate is a chiral, non-natural amino acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. Its value lies in the nitro group, which serves as a versatile precursor for further chemical transformations, and the D-configuration, which is crucial for studying peptide stereochemistry and biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel peptide-based therapeutics, enzyme inhibitors, and chiral catalysts.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel peptide drugs and enzyme inhibitors.
• Chiral Auxiliary/Resolution Agent: Used in asymmetric synthesis and for the separation of enantiomers.
• Biochemical Research: Employed in studies of enzyme mechanisms, receptor binding, and metabolic pathways.
• Peptide Synthesis: Incorporated into custom peptides to study structure-activity relationships (SAR).
• Material Science: Potential monomer for creating specialized polymers with unique optical or electronic properties.
• Agrochemical Research: Investigated as a precursor for developing new active ingredients with specific chiral activity.

Basic Information

Product Name	4-Nitro-D-Phenylalanine Hydrate
CAS No.	444777-67-7
Molecular Formula	C9H10N2O4 • xH2O
Molecular Weight	210.19 (Anhydrous basis)
Synonyms	(2R)-2-Amino-3-(4-nitrophenyl)propanoic acid hydrate; D-4-Nitrophenylalanine hydrate; (R)-2-Amino-3-(4-nitrophenyl)propanoic acid hydrate; p-Nitro-D-phenylalanine hydrate; D-Phenylalanine, 4-nitro-, hydrate; 4-Nitro-D-Phe-OH hydrate
EINECS	Contact for details

Quality Control

Our 4-Nitro-D-Phenylalanine Hydrate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral excess, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (D-isomer)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.