Description

3H-Pyrazol-3-One, 4-[[5-(Diethylamino)-2-Furanyl]Methylene]-2,4-Dihydro-2-Phenyl-5-(Trifluoromethyl)- is a high-value, specialized heterocyclic organic compound featuring a pyrazolone core functionalized with a diethylamino-substituted furan and a trifluoromethyl group. This unique molecular architecture makes it a critical advanced intermediate for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, dyes, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Serves as a precursor in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazolone and trifluoromethyl motifs.
• Dye and Pigment Synthesis: Used in the production of specialized dyes and pigments, where the diethylamino-furan moiety contributes to color properties and light-fastness.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in academic and industrial research to develop molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	3H-Pyrazol-3-One, 4-[[5-(Diethylamino)-2-Furanyl]Methylene]-2,4-Dihydro-2-Phenyl-5-(Trifluoromethyl)-
CAS No.	444190-79-8
Molecular Formula	C19H18F3N3O2
Molecular Weight	377.36 g/mol
Synonyms	4-[(5-Diethylamino-2-furyl)methylene]-2-phenyl-5-(trifluoromethyl)-2,4-dihydropyrazol-3-one; 4-[(5-Diethylaminofuran-2-yl)methylene]-2-phenyl-5-(trifluoromethyl)-2H-pyrazol-3-one; 2,4-Dihydro-4-[[5-(diethylamino)-2-furanyl]methylene]-2-phenyl-5-(trifluoromethyl)-3H-pyrazol-3-one; 5-(Trifluoromethyl)-2-phenyl-4-((5-(diethylamino)furan-2-yl)methylene)-2,4-dihydro-3H-pyrazol-3-one; Advanced Pyrazolone Derivative; Diethylamino-Furan Pyrazolone Trifluoromethyl Intermediate
EINECS	Contact for details

Quality Control

Every batch of this high-purity intermediate is produced and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to ensure it meets the exacting standards required for research and scale-up. Our quality protocols are designed to support GMP/GLP-compliant workflows, ensuring traceability and consistency for critical pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture and contamination. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.