Description

5-{[1-(4-Methoxyphenyl)-1H-Pyrrol-2-Yl]Methylene}-1,3-Dimethyl-2-Thioxodihydro-4,6(1H,5H)-Pyrimidinedione is a sophisticated heterocyclic organic compound, identified by CAS No. 444116-93-2, that serves as a critical advanced intermediate in the synthesis of complex active pharmaceutical ingredients (APIs) and high-value specialty chemicals. Its unique molecular architecture, featuring fused pyrimidinedione and pyrrole rings, makes it a valuable building block for research and development in medicinal chemistry and material science. This product is essential for chemical manufacturers and R&D laboratories focused on developing novel therapeutic agents, agrochemicals, and functional organic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a core scaffold for developing new-generation pesticides and herbicides with enhanced efficacy and selectivity.
• Organic Electronic Materials: Used in research for constructing π-conjugated systems applicable in organic light-emitting diodes (OLEDs) and semiconductor materials.
• Dye & Pigment Synthesis: Intermediate for producing specialized heterocyclic dyes and high-performance pigments.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic synthesis, heterocyclic chemistry, and catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.

Basic Information

Product Name	5-{[1-(4-Methoxyphenyl)-1H-Pyrrol-2-Yl]Methylene}-1,3-Dimethyl-2-Thioxodihydro-4,6(1H,5H)-Pyrimidinedione
CAS No.	444116-93-2
Molecular Formula	C18H17N3O3S
Molecular Weight	355.41 g/mol
Synonyms	5-[(1-(4-Methoxyphenyl)-1H-pyrrol-2-yl)methylene]-1,3-dimethyl-2-thioxo-4,6-dihydro-1H,5H-pyrimidine-4,6-dione; 1,3-Dimethyl-5-{[1-(4-methoxyphenyl)-1H-pyrrol-2-yl]methylene}-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione; 5-((1-(4-Methoxyphenyl)-1H-pyrrol-2-yl)methylene)-1,3-dimethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione; 4,6(1H,5H)-Pyrimidinedione, 5-[(1-(4-methoxyphenyl)-1H-pyrrol-2-yl)methylene]-1,3-dimethyl-2-thioxo-; 444116-93-2; Pyrrolopyrimidinedione derivative; Thioxodihydropyrimidinedione
EINECS	Contact for details

Quality Control

Our 5-{[1-(4-Methoxyphenyl)-1H-Pyrrol-2-Yl]Methylene}-1,3-Dimethyl-2-Thioxodihydro-4,6(1H,5H)-Pyrimidinedione is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for demanding research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.