Description

7-Amino-5-(4-Chlorophenyl)-1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrido[2,3-D]Pyrimidine-6-Carbonitrile is a high-purity, advanced pharmaceutical intermediate belonging to the tetrahydropyridopyrimidine class. This compound is valued for its role as a critical building block in the synthesis of novel, biologically active molecules. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in oncology and antiviral research.

Application

This specialized intermediate serves as a key precursor in several high-value chemical synthesis pathways. Its primary applications include:

• Pharmaceutical Intermediate: A crucial building block for the research and development of new drug candidates, particularly kinase inhibitors.
• Organic Synthesis Research: Used in academic and industrial R&D labs to construct complex heterocyclic frameworks for biological screening.
• Agrochemical Development: Serves as a precursor in the synthesis of novel compounds for crop protection research.
• Biochemical Tool Compound: Utilized in life science research to study specific biological pathways and mechanisms of action.
• Custom Synthesis Projects: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development.

Basic Information

Product Name	7-Amino-5-(4-Chlorophenyl)-1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrido[2,3-D]Pyrimidine-6-Carbonitrile
CAS No.	444116-23-8
Molecular Formula	C₁₇H₁₂ClN₅O₂
Molecular Weight	353.76 g/mol
Synonyms	7-Amino-5-(4-chlorophenyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile; 7-Amino-5-(p-chlorophenyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile; 444116-23-8; Pyrido[2,3-d]pyrimidine-6-carbonitrile, 7-amino-5-(4-chlorophenyl)-1,3-dimethyl-1,2,3,4-tetrahydro-2,4-dioxo-; 1,2,3,4-Tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile, 7-amino-5-(4-chlorophenyl)-1,3-dimethyl-2,4-dioxo-
EINECS	Contact for details

Quality Control

Our 7-Amino-5-(4-Chlorophenyl)-1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrido[2,3-D]Pyrimidine-6-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are available upon request, and we support compliance with relevant regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.