Description

(4-Hydroxy-5,7-Dimethyl-Pyrido[2,3-D]Pyrimidin-2-Ylsulfanyl)-Acetic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the pyridopyrimidine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, including kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, especially those targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Kinase Inhibitor Development: Used in the research and development of novel kinase inhibitors due to the privileged pyridopyrimidine core structure.
• Biochemical Tool Compound: May be utilized in biochemical assays to study enzyme function and cellular signaling mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for fundamental research in organic synthesis and bioorganic chemistry.

Basic Information

Product Name	(4-Hydroxy-5,7-Dimethyl-Pyrido[2,3-D]Pyrimidin-2-Ylsulfanyl)-Acetic Acid
CAS No.	443749-00-6
Molecular Formula	C11H11N3O3S
Molecular Weight	265.29 g/mol
Synonyms	2-[(4-Hydroxy-5,7-dimethylpyrido[2,3-d]pyrimidin-2-yl)thio]acetic acid; (4-Hydroxy-5,7-dimethyl-2-pyrido[2,3-d]pyrimidinylthio)acetic Acid; 4-Hydroxy-5,7-dimethylpyrido[2,3-d]pyrimidine-2-thioacetic acid; 443749-00-6; Pyrido[2,3-d]pyrimidine-2-thioacetic acid derivative
EINECS	Contact for details

Quality Control

Every batch of (4-Hydroxy-5,7-Dimethyl-Pyrido[2,3-D]Pyrimidin-2-Ylsulfanyl)-Acetic Acid is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.