Description

2-{[3-(4-Methylphenyl)-4-Oxo-3,4,5,6,7,8-Hexahydro[1]Benzothieno[2,3-D]Pyrimidin-2-Yl]Sulfanyl}-n-[3-(Trifluoromethyl)Phenyl]Acetamide is a high-purity, complex heterocyclic compound designed for advanced research and development applications. This molecule is valued for its unique structural features, including a fused benzothienopyrimidine core and a trifluoromethylphenyl acetamide moiety, which are critical for modulating biological activity and physicochemical properties. It serves as a key pharmaceutical intermediate or building block for medicinal chemists and process development scientists in the life sciences sector.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Employed in vitro and in vivo to investigate specific biological pathways and protein interactions.
• Process Chemistry Development: Acts as a standard or key material for developing and scaling up efficient synthetic routes in pilot plants.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for cutting-edge research in organic synthesis and chemical biology.

Basic Information

Product Name	2-{[3-(4-Methylphenyl)-4-Oxo-3,4,5,6,7,8-Hexahydro[1]Benzothieno[2,3-D]Pyrimidin-2-Yl]Sulfanyl}-n-[3-(Trifluoromethyl)Phenyl]Acetamide
CAS No.	443740-08-7
Molecular Formula	C28H24F3N3O2S2
Molecular Weight	555.63 g/mol
Synonyms	2-({3-(4-Methylphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl}sulfanyl)-N-[3-(trifluoromethyl)phenyl]acetamide; 2-[[3-(4-Methylphenyl)-4-oxo-5,6,7,8-tetrahydro-3H-[1]benzothieno[2,3-d]pyrimidin-2-yl]thio]-N-[3-(trifluoromethyl)phenyl]acetamide; 443740-08-7; UNII-5J8X8H8E2G; 5J8X8H8E2G; CHEMBL3186668; BDBM50388879; AKOS015915896
EINECS	Contact for details

Quality Control

Our 2-{[3-(4-Methylphenyl)-4-Oxo-3,4,5,6,7,8-Hexahydro[1]Benzothieno[2,3-D]Pyrimidin-2-Yl]Sulfanyl}-n-[3-(Trifluoromethyl)Phenyl]Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP guidelines for advanced intermediates, ensuring reliability for your most sensitive R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.