Description

5-(4-Methoxyphenyl)-2-thioxo-2,3-dihydrothieno[2,3-d]pyrimidin-4(1H)-one is a high-purity, heterocyclic organic compound featuring a fused thienopyrimidinone core, serving as a critical synthetic intermediate and building block in advanced chemical research. Its unique molecular architecture, combining a methoxyphenyl group with a thioxodihydropyrimidinone moiety, makes it a valuable scaffold for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research scientists and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry, drug discovery, and material science.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for targeting various enzyme families and receptors.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a precursor in the research and development of new pesticides and herbicides.
• Organic Synthesis: A versatile intermediate for constructing complex heterocyclic systems and functional molecules in academic and industrial R&D.
• Material Science Precursor: Potential use in the development of organic electronic materials or photoactive compounds due to its conjugated structure.

Basic Information

Product Name	5-(4-Methoxyphenyl)-2-thioxo-2,3-dihydrothieno[2,3-d]pyrimidin-4(1H)-one
CAS No.	443320-58-9
Molecular Formula	C₁₃H₁₀N₂O₂S₂
Molecular Weight	290.36 g/mol
Synonyms	5-(4-Methoxyphenyl)-2-thioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-4-one; 4H-Thieno[2,3-d]pyrimidin-4-one, 1,2,3,4-tetrahydro-5-(4-methoxyphenyl)-2-thioxo-; 5-(p-Methoxyphenyl)-2-thioxo-2,3-dihydrothieno[2,3-d]pyrimidin-4(1H)-one; CAS 443320-58-9; Thieno[2,3-d]pyrimidine derivative
EINECS	Contact for details

Quality Control

Our production of 5-(4-Methoxyphenyl)-2-thioxo-2,3-dihydrothieno[2,3-d]pyrimidin-4(1H)-one adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP-compliant manufacturing for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.