Description

2-((7-(2-Ethoxyethyl)-3-Methyl-2,6-Dioxo-2,3,6,7-Tetrahydro-1H-Purin-8-Yl)Thio)Acetic Acid is a high-purity, advanced pharmaceutical intermediate with a complex purine-thioacetic acid structure. This compound is valued for its role as a critical building block in the synthesis of novel therapeutic agents, particularly in oncology and antiviral research. It is primarily required by R&D laboratories, custom synthesis providers, and pharmaceutical manufacturers developing next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel purine-based active pharmaceutical ingredients (APIs).
• Oncology Drug Discovery: Used in research and development of targeted cancer therapies and kinase inhibitors.
• Antiviral Agent Synthesis: Serves as a building block for compounds with potential activity against viral pathogens.
• Biochemical Research: Employed as a reference standard or probe in enzymatic and receptor binding studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific novel chemical entities (NCEs).
• Academic Research: Utilized in university and institutional labs for medicinal chemistry and organic synthesis projects.

Basic Information

Product Name	2-((7-(2-Ethoxyethyl)-3-Methyl-2,6-Dioxo-2,3,6,7-Tetrahydro-1H-Purin-8-Yl)Thio)Acetic Acid
CAS No.	442865-12-5
Molecular Formula	C₁₂H₁₆N₄O₅S
Molecular Weight	328.34 g/mol
Synonyms	8-Mercaptopurine-1-oxide ethoxyethyl acetic acid derivative; 2-[(7-(2-Ethoxyethyl)-3-methyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-8-yl)thio]acetic acid; 8-Thioacetic acid derivative of 7-(2-ethoxyethyl)theophylline; (7-(2-Ethoxyethyl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)thioacetic acid; 442865-12-5; Purine-8-thioacetic acid derivative
EINECS	Contact for details

Quality Control

Our 2-((7-(2-Ethoxyethyl)-3-Methyl-2,6-Dioxo-2,3,6,7-Tetrahydro-1H-Purin-8-Yl)Thio)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with full chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.