Description

2,4-Dichloro-7-(2-Trimethylsilanyl-Ethoxymethyl)-7H-Pyrrolo[2,3-D]Pyrimidine is a high-value, multi-functional heterocyclic building block primarily used in advanced organic synthesis. This compound is critical for the development of novel pharmaceutical agents, particularly kinase inhibitors and other targeted therapeutics. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Agrochemical Research: Serves as a building block for developing new active ingredients with potential herbicidal or pesticidal properties.
• Chemical Biology: Used in the design and synthesis of molecular probes for studying enzyme function and cellular signaling processes.
• Material Science: Potential monomer or precursor for creating specialized polymers and advanced organic electronic materials.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring complex pyrrolopyrimidine scaffolds.

Basic Information

Item	Details
Product Name	2,4-Dichloro-7-(2-Trimethylsilanyl-Ethoxymethyl)-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	442847-52-1
Molecular Formula	C₁₂H₁₇Cl₂N₃OSi
Molecular Weight	318.27 g/mol
Synonyms	2,4-Dichloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine; 2,4-Dichloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine; 7-((2-(Trimethylsilyl)ethoxy)methyl)-2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine; 2,4-Dichloro-7-(2-TMS-ethoxymethyl)-7H-pyrrolo[2,3-d]pyrimidine; 2,4-Dichloro-7-(2-trimethylsilylethoxymethyl)-7H-pyrrolo[2,3-d]pyrimidine; 2,4-Dichloro-7-SEM-7H-pyrrolo[2,3-d]pyrimidine; 2,4-Dichloro-7-(SEM)-7H-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-7-(2-Trimethylsilanyl-Ethoxymethyl)-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.