Description

2-(2-Imidazo[1,2-A]Pyrimidin-2-Ylethyl)-1H-Isoindole-1,3(2H)-Dione is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of target drug molecules, especially those with imidazopyrimidine or isoindole motifs.
• Drug Discovery & Medicinal Chemistry: Used in research laboratories for constructing compound libraries and exploring structure-activity relationships (SAR) for new therapeutic agents.
• API Synthesis: Integral in the production route for potential APIs targeting central nervous system (CNS) disorders, inflammatory diseases, or oncology.
• Biochemical Research: Employed as a tool compound or a standard in analytical method development and validation within R&D settings.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or non-GMP conditions.

Basic Information

Product Name	2-(2-Imidazo[1,2-A]Pyrimidin-2-Ylethyl)-1H-Isoindole-1,3(2H)-Dione
CAS No.	442667-35-8
Molecular Formula	C₁₆H₁₂N₄O₂
Molecular Weight	292.30 g/mol
Synonyms	1H-Isoindole-1,3(2H)-dione, 2-[2-(imidazo[1,2-a]pyrimidin-2-yl)ethyl]-; 2-[2-(Imidazo[1,2-a]pyrimidin-2-yl)ethyl]isoindoline-1,3-dione; Imidazo[1,2-a]pyrimidine-2-ethylphthalimide; CAS 442667-35-8
EINECS	Contact for details

Quality Control

Our production of 2-(2-Imidazo[1,2-A]Pyrimidin-2-Ylethyl)-1H-Isoindole-1,3(2H)-Dione adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications for pharmaceutical R&D use. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.