Description

Propanoic Acid, 2-[(5,6-Dimethylthieno[2,3-D]Pyrimidin-4-Yl)Thio]- is a high-purity, advanced pharmaceutical intermediate characterized by its unique thioether-linked thienopyrimidine scaffold. This compound matters for its critical role as a key building block in the synthesis of novel, targeted therapeutic agents, offering researchers precise control over molecular structure and activity. It is primarily needed by pharmaceutical R&D and process chemistry teams developing next-generation small molecule drugs, particularly in oncology and kinase inhibitor programs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of investigational drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to explore new chemical entities.
• Process Development: Serves as a reference standard and starting material for scaling up API (Active Pharmaceutical Ingredient) manufacturing processes under GMP conditions.
• Biochemical Tool Compound: Utilized in vitro to study enzyme inhibition and cellular signaling pathways relevant to disease mechanisms.
• Custom Synthesis Building Block: Employed by fine chemical suppliers for the contract manufacturing of specialized, high-value compounds.

Basic Information

Product Name	Propanoic Acid, 2-[(5,6-Dimethylthieno[2,3-D]Pyrimidin-4-Yl)Thio]-
CAS No.	442571-27-9
Molecular Formula	C13H14N2O2S2
Molecular Weight	294.39 g/mol
Synonyms	2-[(5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl)thio]propanoic acid; 4-[(1-Carboxyethyl)thio]-5,6-dimethylthieno[2,3-d]pyrimidine; 5,6-Dimethyl-4-((1-carboxyethyl)thio)thieno[2,3-d]pyrimidine; Thieno[2,3-d]pyrimidine-4-thiol, 5,6-dimethyl-, 2-propanoate; CAS 442571-27-9
EINECS	Contact for details

Quality Control

Our Propanoic Acid, 2-[(5,6-Dimethylthieno[2,3-D]Pyrimidin-4-Yl)Thio]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive compound.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.