Description

7-Bromo-2-(Chloromethyl)-4H-Pyrido[1,2-A]Pyrimidin-4-One is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because it provides a versatile scaffold for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromo and chloromethyl functionalities into their target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and kinase inhibitors.
• Agrochemical Research: Serves as a core structure for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Used in the research and development of advanced organic electronic materials and photoactive compounds.
• Chemical Biology: Employed as a molecular probe or a tagging reagent in proteomics and bio-conjugation studies.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and heterocycle functionalization.

Basic Information

Product Name	7-Bromo-2-(Chloromethyl)-4H-Pyrido[1,2-A]Pyrimidin-4-One
CAS No.	442531-33-1
Molecular Formula	C9H6BrClN2O
Molecular Weight	273.51 g/mol
Synonyms	7-Bromo-2-(chloromethyl)pyrido[1,2-a]pyrimidin-4-one; 4H-Pyrido[1,2-a]pyrimidin-4-one, 7-bromo-2-(chloromethyl)-; 2-(Chloromethyl)-7-bromo-4H-pyrido[1,2-a]pyrimidin-4-one; 7-Bromo-2-chloromethyl-4H-pyrido[1,2-a]pyrimidin-4-one; CAS 442531-33-1
EINECS	Contact for details

Quality Control

Our 7-Bromo-2-(Chloromethyl)-4H-Pyrido[1,2-A]Pyrimidin-4-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.