Description

[3',5'-Di-(Trifluoromethyl)-Biphenyl-4-Yl]-Methanol is a high-value fluorinated biphenyl derivative, serving as a critical advanced pharmaceutical intermediate and building block in modern synthetic chemistry. Its molecular structure, featuring multiple trifluoromethyl groups, is engineered to impart enhanced metabolic stability and lipophilicity to target molecules. This compound is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used to construct fluorinated active ingredients for advanced pesticides and herbicides, leveraging the fluorine effect for improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display and lighting materials, where stability and performance are critical.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and other transformations to introduce the biaryl-methanol motif into more complex molecular architectures.
• Material Science Research: Investigated for the development of novel polymers and specialty chemicals with unique surface properties and chemical resistance.

Basic Information

Product Name	[3',5'-Di-(Trifluoromethyl)-Biphenyl-4-Yl]-Methanol
CAS No.	442514-47-8
Molecular Formula	C15H10F6O
Molecular Weight	320.23 g/mol
Synonyms	[3',5'-Bis(trifluoromethyl)[1,1'-biphenyl]-4-yl]methanol; (3',5'-Bis(trifluoromethyl)biphenyl-4-yl)methanol; 4-(Hydroxymethyl)-3',5'-bis(trifluoromethyl)-1,1'-biphenyl; 3',5'-Di(trifluoromethyl)-4-biphenylmethanol; Biphenyl-4-ylmethanol, 3',5'-bis(trifluoromethyl)-; CAS 442514-47-8
EINECS	Contact for details

Quality Control

Our production of [3',5'-Di-(Trifluoromethyl)-Biphenyl-4-Yl]-Methanol adheres to stringent internal quality standards, ensuring batch-to-batch consistency for critical R&D and scale-up processes. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support customer audits and can provide material to meet specific project requirements under a Quality Agreement.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.